We focus on the following research areas:
1. Develop bioinformatics tools, databases and analysis platforms for high-throughput data .
Tian F*, Shah PK*, Liu X, Negre N, Chen J, Karpenko O, White KP, Grossman RL. Flynet: a genomic resource for Drosophila melanogaster transcriptional regulatory networks. Bioinformatics. 2009 Nov 15;25(22):3001-4.
Tian F, Zhang H, Zhang X, Song C, Xia Y, Wu Y, Liu X. miRAS: a data processing system for miRNA expression profiling study. BMC Bioinformatics. 2007 Aug 4;8(1):285.
2. AI based medical big data research and application, including Natural Language Processing (NLP) and Geographic Information System (GIS).
X. Zhang, H. Zhang, L. Sheng and F. Tian*, "DL-PER: Deep Learning Model for Chinese Prehospital Emergency Record Classification," in IEEE Access, vol. 10, pp. 64638-64649, 2022, doi: 10.1109/ACCESS.2022.3179685.
Pre hospital emergency information processing device. Invention patent: ZL 2021 1 0996694.9
3. Multi-omics data analysis pipeline and algorithm development.
Xu W*, Tian F*, Tai X, Song G, Liu Y, Fan L, Weng X, Yang E, Wang M, Bornhäuser M, Zhang C, Lock RB, Wong JWH, Wang J, Jing D, Mi JQ. ETV6::ACSL6 translocation-driven super-enhancer activation leads to eosinophilia in acute lymphoblastic leukemia through IL-3 overexpression. Haematologica. 2024 Feb 15. doi: 10.3324/haematol.2023.284121 [Epub ahead of print]
Software copyright registration, 2024SR0197619, et al.
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